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Science ignores the spiritual realm because it is not amenable to scientific analysis. As importantly, the predictive success of Newtonian theory, emphasizing the primacy of a physical Universe, made the existence of spirit and God an extraneous hypothesis that offered no explanatory principles needed by science.

What the founders of modern science ... had to do, was not criticize and to combat certain faulty theories, and to correct or to replace them by better ones. They had to do something quite different. They had to destroy one world and replace it by another. They had to reshape the framework of our intellect itself, to restate and to reform its concepts, to evolve a new approach to Being, a new concept of knowledge, and a new concept of science - and even to replace a pretty natural approach, that of common sense, by another which is not natural at all.

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