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What happened with the opioid epidemic is the Mexican cartels made a very deliberate, corporate decision to undercut the price of opioids. What they discovered was they could increase production, increase potency and decrease the price, and sell it for a third of what the Big Pharma could, or street dealers could, for Big Pharma pills. North America, and to a slightly lesser extent Europe, is being flooded with this Mexican heroin as a direct result of the attempt to undercut American pharmaceutical companies.