When authorities warn you of the sinfulness of sex, there is an important lesson to be learned. Do not have sex with the authorities.

In 'Futurama,' the skin color is no longer yellow. They have actually evolved to cartoon skin tone. But they still have four fingers.

Of course I’ve gone mad with power! Have you ever tried going mad without power? It’s boring and no one listens to you! — Russ Cargill

Love is a snowmobile racing across the tundra and then suddenly it flips over, pinning you underneath. At night, the ice weasels come.

The tendency in comedy is to have a character who's stupid get more stupid, because you're trying to top yourself and not just repeat.

I judge my life by how miserable it used to be. If I could pay my rent, I was deliriously happy. Now I'm deliriously happy all the time.

I also found child's play - stuff that was not considered serious, but goofy - was the stuff I liked to do, so I still do it as an adult.

I’ll keep it short and sweet - Family. Religion. Friendship. These are the three demons you must slay if you wish to succeed in business.

People go into cartooning because they're shy and they're angry. That's when you're sitting in the back of a classroom drawing the teacher.

We've got a bunch of new writers now who tell me they grew up watching The Simpsons. It's bizarre, and they're writing some very funny stuff.

I think in daily newspapers, the way comic strips are treated, it's as if newspaper publishers are going out of their way to kill the medium.

My life changed when I was able to not only get seated in nice restaurants, I was given free appetizers. That was like, "Oh, my God, I've arrived".

Oftentimes, what seems to be a street lunatic charging at me spouting gibberish turns out to be a devoted 'Simpsons' fan quoting their favorite line.

As astute followers of 'Life in Hell' will notice, Akbar and Jeff wear the same striped T-shirt as Charlie Brown. 'Peanuts' was very important to me.

You just have to keep in mind that the important relationship is the relationship with the audience. That's what I try to do. Everything else is secondary.

Today is the first day of the rest of your short, brutish existence as a sentient creature before being snuffed out into utter nothingness for all eternity.

Sometimes people get mad at The Simpsons' subversive story telling, but there's another message in there, which is a celebration of making wild, funny stories.

I've conducted an experiment on my kids. Instead of denying them access to media, I've encouraged it. They read comic books, play Nintendo and watch way too much TV.

Humor does depend on surprise, and the things that people remember as the funniest things in the world, you look at later and you go, "What? What was that all about?"

America's health care system is second only to Japan, Canada, Sweden, Great Britain, well ... all of Europe. But you can thank your lucky starts we don't live in Paraguay!

I think when 'The Simpsons' first came on, there was an uproar. People got used to it. They realized the show's really funny, it's got a heart, so I think it's pretty safe.

I thought I was going to make crazy cartoons for the rest of my life. I didn't think I'd ever get paid for it, didn't think I drew well enough, but I knew it made me happy.

With animation because you can draw anything and do anything and have the characters do whatever you want the tendency is to be very loose with the boundaries and the rules.

Solitude never hurt anyone. Emily Dickinson lived alone, and she wrote some of the most beautiful poetry the world has ever known... then went crazy as a loon." Lisa Simpson

If I have one technology tip of the day, it's this: No matter how good the video on YouTube is, don't read the comments, just don't, because it will make you hate all humans.

'Adult Swim' on the Cartoon Network is unbelievable. And 'South Park' continues to do great stuff. And 'Family Guy' and the various other Seth MacFarlane projects are amazing.

Since I was there in the very beginning, I know the history of the characters. So, I make comments about the tone and sometimes remind the writers that we've done that before.

With animation, because you can draw anything and do anything and have the characters do whatever you want, the tendency is to be very loose with the boundaries and the rules.

I've loved science fiction ever since I was a little kid, mainly from looking at the covers of science-fiction magazines and books, and I've read quite extensively as an adult.

I plead alignment to the flakes of the untitled snakes of a merry cow and to the republicrats for which they scam: one nacho, underpants with licorice and jugs of wine for owls.

I draw a weekly comic strip called Life in Hell, which is syndicated in about 250 newspapers. That's what I did before The Simpsons, and what I plan to do for the rest of my life.

One of the things I would like to do is make up stories that I would have enjoyed when I was a kid. So, if I'm thinking about an audience, it's usually a younger version of myself.

I went to Bali, and I was in a small village, and somebody who was with me showed a woman a little figurine of Bart and asked: 'Do you know who this is?' And she said: 'Mickey Mouse.'

I'm presently incarcerated. Convicted of a crime I didn't even commit. Hah! "Attempted murder"? Now honestly, what is that? Do they give a Nobel prize for attempted chemistry? Do they?

I think people who work in comedy and humor are hesitant to analyze it too much, because you feel like if you take it apart, you'll break it and not be able to put it back together again.

I gave away 'Life in Hell' when it was a little 'zine, and sold it at record stores for $1, and I knew from the time that I first did it that I would continue to do it, because it was fun.

I have less to do with 'The Simpsons' every season, but I stick my nose in here and there. Basically, it's just trying to keep the characters consistent and making sure the show has a soul.

A lot of people believe that if everybody just did what they were told - obeyed - everything would be fine. But that's not what life is all about. That's not real. It's never going to happen.

The best stories in our culture have some sort of subversiveness - Mark Twain, 'Catcher in the Rye.' You provide kids with great stories and teach them how to use the tools to make their own.

The writers led by Mike Scully are fantastic. And they're creating original stories that not only don't repeat what we've already done, they also don't repeat anything I've seen on television.

The really great thing about having two TV shows going on at the same time is that I can go to one and say that I have to go and visit the other and then I can just go home and they don't know.

The really great thing about having two TV shows going on at the same time is that I can go to one and say that I have to go and visit the other, and then I can just go home, and they don't know.

One of the great things about the Internet is that you can read what everybody has to say about everything. It is fascinating to me, the critiques about humor by people who have no sense of humor.

The thing that makes me happiest about Simpsons Illustrated are all the drawings that we get from readers. I wish we could print them all. They're really imaginative. They show a lot of hard work.

The scary thing about the future... there will be tiny cameras everywhere, and they'll be flying around like mosquitoes and drones. That will be bad. Drones are scary. You can't reason with a drone.

If something is too hard to do, then it's not worth doing. You just stick that guitar in the closet next to your shortwave radio, your karate outfit and your unicycle and we'll go inside and watch TV.

'The Simpsons' obviously is a huge success, and Fox has nothing to do with its success, with its creative success, and as a result they don't really like the show. They don't like 'The Simpsons' at Fox.

I love the idea that we put in jokes the kids don't get. And that later, when they grow up and read a few books and go to college and watch the show again, they can get it on a completely different level.

I think there is a certain charm to the hand drawn image that I like. My problem with CGI is that it's so rich in texture that my eyes actually get tired. Everything is in focus down to the littlest leaf.

When The Simpsons came around, there really was nothing else like it on TV. It's hard to imagine, but when Fox first took the plunge with it, it was considered controversial to put animation on prime time.

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