I'm quite worried about the fiscal imbalances that we've got and what that might mean in terms of financial crisis ahead.

Two out of every five people on Earth today owe their lives to the higher crop outputs that fertilizer has made possible.

The typical project design time for a large company like IBM - and they keep track of this - is a little over four years.

Sometimes we do get taken by surprise. For example, when the Internet came along, we had it as a fifth or sixth priority.

Eventually we'll be able to sequence the human genome and replicate how nature did intelligence in a carbon-based system.

It's an experiment, and it's probably good to have a couple states try it out to see before you make that national policy.

Some people read off of their Palms and Pocket PCs, but the real immersible reading experience takes a full-screen device.

The most meaningful way to differentiate your company from your competition, is to do an outstanding job with information.

I can understand wanting to have millions of dollars; there's a certain freedom, meaningful freedom, that comes with that.

Nigeria has moved into low-middle-income, but their north is very poor, and the health care systems there have broken down.

There were a lot of missteps in the early days, but because we got in early we got to make more mistakes than other people.

I was lucky to be involved and get to contribute to something that was important, which is empowering people with software.

Our work in global health is about things like cutting childhood deaths, and every year we continue to make progress there.

When you program, you want to think you're writing the best possible program for the... for the task you're trying to solve.

An important re-engineering principle is that companies should focus on their core competence and outsource everything else.

Everyone needs a coach. It doesn't matter whether you're a basketball player, a tennis player, a gymnast or a bridge player.

The outpouring of support from millions of people in the immediate aftermath of the earthquake in Haiti has been impressive.

In inner-city, low-income communities of color, there's such a high correlation in terms of educational quality and success.

In the decade ahead I can predict that we will provide over twice the productivity improvement that we provided in the '90s.

My experience of malaria was just taking anti-malarials, which give you strange dreams, because I don't want to get malaria.

It is hard to overstate how valuable it is to have all the incredible tools that are used for human disease to study plants.

I have a particular relationship with Vinod Khosla because he's got a lot of very interesting science-based energy startups.

It's possible - you can never know - that the universe exists only for me. If so, it's sure going well for me, I must admit.

Only a few businesses will succeed by having the lowest price, so most will need a strategy that includes customer services.

A lot of the things that will really improve the world fortunately aren't dependent on Washington doing something different.

There will be two types of businesses in the next 5 years, those that are on the Internet, and those that are out of business

Microsoft has had many, many successful products. I'm committed to one company. This is the industry I've decided to work in.

The information society should serve all of its citizens, not only the technically sophisticated and economically privileged.

I can understand wanting to have a million dollars but once you get beyond that, I have to tell you, it's the same hamburger.

Like a human being, a company has to have an internal communication mechanism, a "nervous system", to coordinate its actions.

I would certainly use my voice to try and avoid anything that undermines confidence, so that parents are using vaccines fully.

I think when smallpox was eliminated, the whole world got pretty excited about that because it’s just such a dramatic success.

I think when smallpox was eliminated, the whole world got pretty excited about that because it's just such a dramatic success.

There are ecosystems like coral reefs [at risk] through ocean acidification. Those are valuable things that we should protect.

The advance of technology is based on making it fit in so that you don't really even notice it, so it's part of everyday life.

You will NOT make $60,000 a year right out of high school. You won't be a vice-president with a car phone until you earn both.

I'm a big believer that as much as possible, and there's obviously political limitations, freedom of migration is a good thing.

My dream is that every child has enough food to eat, good medical care, and the chance to go to school and even attend college.

Unemployment rates among Americans who never went to college are about double that of those who have a postsecondary education.

Don't let complexity stop you. Be activists. Take on the big inequities. It will be one of the great experiences of your lives.

Until we're educating every kid in a fantastic way, until every inner city is cleaned up, there is no shortage of things to do.

Globalization has made copper and other minerals more valuable, and Ghana and Kenya have recently discovered mineral resources.

Most of our competitors were one-product wonders... They would do their one product, but never get their engineering sorted out.

In almost every job now, people use software and work with information to enable their organization to operate more effectively.

In almost every job now, people use software and work with information to enable their organisation to operate more effectively.

The belief that the world is getting worse, that we can't solve extreme poverty and disease, isn't just mistaken. It is harmful.

In the same way that when the car got going, people thought it would be an electric car, people thought it would be a steam car.

Harnessing steam power required many innovations, as William Rosen chronicles in the book 'The Most Powerful Idea in the World.'

Instead of buying airplanes and playing around like some of our competitors, we've rolled almost everything back to the company.

It's pretty amazing to go from a world where computers were unheard of and very complex to where they're a tool of everyday life.

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