Nothing good comes out of depression.

Look to the living, love them, and hold on.

We all move uneasily within our restraints.

Without science, there would be no such hope.

Knowledge is marvelous, but wisdom is even better.

Grief comes and goes, but depression is unremitting

Grief comes and goes, but depression is unremitting.

I am reminded of the importance of small kindnesses.

Suicide is not a blot on anyone’s name; it is a tragedy

With grief, you have reason to despair; it's a human thing.

Confidentiality is an ancient and well-warranted social value.

An ardent temperament makes one very vulnerable to dreamkillers.

'An Unquiet Mind' wasn't hard to write in terms of the actual writing of it.

I say I'm an academic: a professor of psychiatry at Johns Hopkins. And I write.

The complexities of what we are given in life are vast and beyond comprehension.

Exuberance is a gift of grace that allows us to move on, to seek, to love again.

Suicide Note: The calm, Cool face of the river Asked me for a kiss. -Langston Hughes

Most people don't have the advantage of being able to evaluate their doctor in advance.

Scientists have made extraordinary advances in understanding the brain and its disorders.

Love has, at its best, made the inherent sadness of life bearable, and its beauty manifest.

Love, like life, is much stranger and far more complicated than one is brought up to believe.

We expect well-informed treatment for cancer or heart disease; it matters no less for depression.

Everyone has good cause for suicide, or at least it seems that way to those who search for it. (74)

One of the advantages of science is that one's work, ultimately, is either replicated or it is not.

Moods are complicated and very much a part of who we are. People would be very boring without them.

Mania is as bad as it gets. If not treated, it will become worse, more frequent, and harder to treat.

Nature is the first tutor. No one remains untouched or unschooled by the earth, seasons, and heavens.

There are relatively few things that kill people that are young other than car accidents and suicide.

A possible link between 'madness' and genius is one of the oldest and most persistent of cultural notions.

Anyone who suggests that coming back from suicidal despair is a straightforward journey has never taken it.

There are a lot of studies that suggest a higher rate of creativity in bipolars than the general population.

Chaos and intensity are no substitute for lasting love, nor are they necessarily an improvement on real life.

There are scientists all around the world looking for the genes responsible for bipolar illness and major depression.

Suicide carries in its aftermath a level of confusion and devastation that is, for the most part, beyond description.

I love animals, and I was always attracted to the idea of being a zoo veterinarian or a veterinarian with the circus.

If I can't feel, if I can't move, if I can't think, and I can't care, then what conceivable point is there in living?

But, with time, one has encountered many of the monsters, and one is increasingly less terrified of those still to be met.

In some cases, some people do get depressed in the middle of their grief and they really need to be treated for depression.

In some cases, some people do get depressed in the middle of their grief, and they really need to be treated for depression.

I realized that it was not that I didn’t want to go on without him. I did. It was just that I didn’t know why I wanted to go on

I am a huge advocate of prescription drugs given wisely and for the right reasons and the right diagnosis and also psychotherapy.

I think wanting to write is a fundamental sign of disease and discomfort. I don't think people who are comfortable want to write.

I had been simply treating water, settling on surviving and avoiding pain rather than being actively involved in seeking out life.

The ancient dialogue between reason and the senses is almost always more interestingly and passionately resolved in favor of the senses.

I think people don't understand how intimately tied suicide is to mental illness, particularly to depressive illness and bipolar illness.

One of things so bad about depression and bipolar disorder is that if you don't have prior awareness, you don't have any idea what hit you.

I am tired of hiding, tired of misspent and knotted energies, tired of the hypocrisy, and tired of acting as though I have something to hide.

Somehow, like so many people who get depressed, we felt our depressions were more complicated and existentially based than they actually were.

Grief is so human, and it hits everyone at one point or another, at least, in their lives. If you love, you will grieve, and that's just given.

Never once, during any of my bouts of depression, had I been inclined or able to pick up a telephone and ask a friend for help. It wasn't in me.

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