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In 1999, Purdue Pharma the maker of OxyContin went on a massive marketing campaign. Back then, prescription opioids were only used in extreme cases - post surgery, end of life care, cancer pain. We use a clip from an ad in the film where they had a doctor saying, "Less than 1 percent of people who use prescription opioid long-term will become addicted" - that changed the mindset of physicians across the country.