Sex is a big question mark. It is something people will talk about forever.

I brought one big question with me to Harvard. Why do smart companies fail?

The big question is whether you are going to be able to say a hearty yes to your adventure.

There was a big question as to whether or not different generations have grown up differently.

The big question society will have to answer is whether it wants computers thinking like humans.

The big question is: When will the term structure of interest rates change? That's the question to be worried about.

Climbing, for me, is all about solving the magnitude of the problem. The best projects are the ones with big question marks hanging over them.

I don't pay that much attention to sales figures or awards. To me, the big question is: 'Did you influence the next generation?' That's my goal.

If you go back to the really long-run questions that interested me, the big question was why, over the centuries, the millennia, has growth been speeding up?

The big question about how people behave is whether they've got an Inner Scorecard or an Outer Scorecard. It helps if you can be satisfied with an Inner Scorecard.

One big question that's come up is: Has autism increased on the mild side of things? I don't think so - they've always been here. Some of this is increased detection.

What strikes me - we're apparently at the mercy of an economic system that will never work and the big question is, how do we change it, not how do we put up with it.

If someone has something they're really passionate about, that's their brilliance, and my big question is how do we grow that passion/brilliance and/or help them grow.

The big question for me is - are the players happy? Because in my mind it is all about building the right relationship with your players and creating the right atmosphere.

This is the big question that we all have about our children: How much, how soon, do we tell our children the less comfortable facts about the world they're going to inherit?

And the big question for the West, of course, and to the Europeans is, what other countries, which were formerly part of the Soviet bloc, should be incorporated into western institutions?

After the 9/11 incidents, Islam has become a big question mark among westerners, especially Americans. The mass media constantly raise the issue of relationship between Islam and terrorism.

When I first started doing press interviews, the big question was, 'Do you think women are funny?' People would ask you that in an interview. In an interview! It's like, of course they are.

Most young people want to get out of the environment they grow up in, move on, and do something. The big question for everyone is what they want to do and how. It's something that most young people feel.

When I think about how badly I wanted to be a player, and how obsessed I was with the game, I think that, for a long time in British tennis, that's been a big question mark with the kids, how much they want it.

Now the big question is if you are going to go to all the trouble of setting an opera and making all that music and so on, there's got to be some aspect that you can do in an opera that really makes it worth while.

Philanthropists today want input into how their monies are being deployed. The big question is, can governments use this insight to sell the rich the idea of paying more tax rather than spend more on charitable giving?

Everybody who goes through the business will make mistakes. The big question is how big will the mistakes be? How fast will they learn from the mistakes, and how quickly will they get the business in the correct direction?

I love to get to that place where I don't know what kind of music I'm doing; I don't know if it's any good. I don't know if it's anything. It's a big question mark. The idea is to have interesting results. That's my bottom line.

I think it's really important to give yourself a very big question that you're working on that you can come home to, even if you, you know, are going to have to go without a cup of coffee or even a meal, that that should nourish you.

Where we are going as a species is a big question. Human evolution certainly hasn't stopped. Every time individuals produce a new zygote, there's a reshuffling and recombination of genes. And we don't know where all of that is going to take us.

I was fortunate enough to have been raised to a certain point before I got into the race thing. I had other views of what a human is, so I was never able to see racism as the big question. Racism was horrendous, but there were other aspects to life.

What scares me? Oh, now that's a big question. I don't know what scares me - cockroaches, nuclear apocalypse. Fear is an interesting thing. It has a place in all of our lives. I try to be as fearless as possible. I don't always succeed, but I like to think I try.

It's the big question of every TV show, right, where you have these two people who it's clear the world wants to put them together and everyone wants to see them together, but also when you're telling these stories you can't throw these people together immediately.

The big question is always, 'Eyes or lips?' I tend to go with the eyes because I've got a lot more material to work with now - and it saves me from reapplying lipstick! I'm a pretty low-maintenance person and it's too excessive to exaggerate both the eyes and lips.

It's always the big question in our lives if you have a lot of success. What do you do with it? Buy more houses, buy more cars, buy more stuff, be wealthy and distant and unengaged? Or do you take all that good fortune that has come towards you and spread the love, do something with it?

It's important that people are open. Some people say, 'I'm going to be a doctor,' and they're a really good doctor. But for the rest of us, it's a big question mark. Just giving yourself a break, letting yourself try new things, and when something doesn't work out, moving along... it's all we can really do.

The big question on everyone's mind is, 'Did Tim Donaghy fix games?' The answer is no. I didn't need to fix them. I usually knew which team was going to win based on which referees had been assigned to the game, their personalities, and the relationships they had with the players and coaches of the teams involved.

What Stieg Larsson was up to - it was the Swedish guilt over World War II. All of our neighbors had the most terrible experiences with the bad forces, but Sweden didn't. I think we use the thrillers in a different way. We never write a thriller like 'Who is the murderer?' The big question in most of our thrillers is... 'Why?'

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