Quotes by Bruce Beutler - Page 1

I grew up hoping that my father might win a Nobel Prize.
Bruce Beutler /
Nobel
Nobel Prize
Prize
Hoping
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If you really want to isolate a disease, then you have to isolate the people who carry it.
Bruce Beutler /
Disease
People Who Want
Isolate
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If we think of the immune system as a machine, then we are far from even knowing all of its parts.
Bruce Beutler /
Immune
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Science is far from the center of the world for most people: even for many with highly sophisticated tastes, interests, and accomplishments.
Bruce Beutler /
Sophisticated
Science World People
Accomplishments
Center
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In college, I had an early introduction to classical genetics from Professor Dan Lindsley, also an extraordinary teacher who influenced me greatly.
Bruce Beutler /
Extraordinary
Genetics
Introduction
Classical
Dan
Greatly
Influenced
Professor
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My idea right from the beginning, I guess, was to dismantle the immune system one gene at a time so we could track the mutations that cause problems.
Bruce Beutler /
Immune
Track
Dismantle
Gene
Mutations
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People may have said that without symptoms, you can't transmit Ebola. I'm not sure about that being 100 percent true. There's a lot of variation with viruses.
Bruce Beutler /
Symptoms
Transmit
Variation
Viruses
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Chance leads to discoveries, and mutagenesis is a way to enhance one's chances of finding a surprise. Often it is the exceptional observations that lead to advances; once you understand exceptions, you understand the whole picture.
Bruce Beutler /
Surprise
Advances
Chances
Discoveries
Enhance
Exceptions
Leads
Observations
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The nicest part of the prize, perhaps, is the effect on my friends and family. Each of them feels proud and happy to have the relationship with me that they do. In a way, it's as though they received an award too, and I like that very much.
Bruce Beutler /
Prize
Family Relationship Me
Award
Friends And Family
Received
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Autoimmunity is probably the next frontier. The majority of cases of autoimmune disease result from a complex genetic problem that has environmental influences. It is a colossal task for the immune system to maintain tolerance to self and yet be ready to react to everything in the world around us.
Bruce Beutler /
Environmental
Cases
Colossal
Disease
Immune
Majority
Next
Problem
Ready
Tolerance
Around
Complex
Frontier
Genetic
Influences
Maintain
React
Result
System
Task
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A mutation can create an alternative form of a phenomenon - a phenotype or trait - and we can learn a lot by seeing this alternative state. Once I saw a mouse with no eyelids. It simply had a membrane over the eyes. I found it fascinating that there is a single gene required for eyelids to develop.
Bruce Beutler /
Fascinating
Mutation
Phenomenon
Alternative
Trait
Gene
Mouse
Required
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I felt I ought not to be wasting time, and I hurried to graduate from high school to enroll at UCSD. I also hurried to finish college, to go on to higher studies. By the time I was in my teens, I had a strong sense of mission, wanting to discover something important or solve a major problem in biology or medicine.
Bruce Beutler /
Biology
Higher
Medicine
Ought
Solve
Teens
Wasting Time
By The Time
Discover
Enroll
Finish
Graduate
Major
Mission
Major Problem
Strong Sense
Wanting
Wasting
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