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  • Here is the mistake of the cut-and-dried man of culture. He goes about with the secret of having learned to appreciate the "grandstyle." He has lived in Homer till he can recall the roll of that many-sounding sea. He has pored over the lofty and pictorial thought of Plato till he begins to pique himself upon its grandeur. His fancy has been fed on the quaint old-world genius of Herodotus, his judgment on the melancholy wisdom of Tacitus and the complacent cynicism of Gibbon--and of all this he is conscious and proud.

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Here is the mistake of the cut-and-dried man of culture. He goes about with the secret of having learned to appreciate the "grandstyle." He has lived in Homer till he can recall the roll of that many-sounding sea. He has pored over the lofty and pictorial thought of Plato till he begins to pique himself upon its grandeur. His fancy has been fed on the quaint old-world genius of Herodotus, his judgment on the melancholy wisdom of Tacitus and the complacent cynicism of Gibbon--and of all this he is conscious and proud.

The hybridoma technology was a by-product of basic research. Its success in practical applications is to a large extent the result of unexpected and unpredictable properties of the method. It thus represents another clear-cut example of the enormous practical impact of an investment in research which might not have been considered commercially worthwhile, or of immediate medical relevance. It resulted from esoteric speculations, for curiosity's sake, only motivated by a desire to understand nature.
There are really two things that drive New Year's resolution success. Number one is telling somebody about your goal. Chances are, they'll either join you in pursuing it or at least support you. Number two is to be concrete and specific. You don't want a goal like "becoming a better person," because there's no objective way to judge that. It's got to be something like "I'm going to call my mother once a week." Or "I'm going to cut my body mass index to 25." It can't be fudgeable.

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