Business has to change the way it does business, or we will make no significant changes in the way we relate to the earth.

I've had to step up when I was Al Gore's campaign manager. I had to make significant changes as we moved from Washington, D.C. to Tennessee.

There are some very significant changes in the way the fluids are distributed in our body, the way our heart functions initially, and as well as our bone and muscle.

They emphasize the viewpoint that the protracted economic stagnation in Japan derives from incomplete economic adjustments to significant changes in relative prices.

I think it is fair to say that it is under a great deal of stress, and if I am asking for significant changes, it is because the world is going through significant changes.

You have to get outside of your comfort zone if you're going to make significant changes in your life, and since few things scare people like the unknown, feeling fear is an excellent sign that you're on the right track.

If we are ever going to fix our housing affordability crisis, we have to make significant changes to how we plan and construct, and we have to be open to solutions that make it easier and faster to build much-needed housing.

In theory, it is illegal to make the basement into a bureaucratic purgatory. In 1994, for instance, Congress prohibited agencies from making significant changes in a whistleblower's 'working conditions' as punishment for speaking out.

In my mind, this is an 'and,' it's not 'either' 'or' or 'but.' Yeah, you can feel a certain way about honoring the flag and the country, and feel that there needs to be some significant changes in the system, regarding racial inequalities.

There is a group of entrepreneurs pushing the envelope, government officials that are making significant changes despite the odds, and visionary writers, academics, and colleagues whose work confirms, amplifies, and stretches my own thinking.

In the same period, Polish literature also underwent some significant changes. From social-political literature, which had a great tradition and strong motivation to be that way, Polish literature changed its focus to a psychological rather than a social one.

We do not always appreciate the role the Queen has played in one of the most significant changes in the past 60 years: the transformation of Britain into a multi-ethnic, multi-faith society. No one does interfaith better than the Royal family, and it starts with the Queen herself.

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