We, as individuals, are defined by the choices we make. Some of our decisions can have very significant consequences and totally change the courses of our lives.

We can continue to make significant strides in the scientific community by exploring new stem cell research methods that do not include destroying human embryos.

In all likelihood, a significant amount of time will be required to restore the nearly eight and a half million jobs that were lost nationwide over 2008 and 2009.

In performance capture roles, it's not a committee of animators that author the role, it's the actor. I think that's a significant thing for people to understand.

It is correct that securing the border is a government function, but when the government fails, it has a specific and significant impact on individual landowners.

Most American elementary schools and high schools, and nearly all colleges and universities, teach everything that is significant from a liberal/Left perspective.

'Rent,' for me, was a significant time in my life because it was my first break. It was my first professional job. I also met my husband in that cast, Taye Diggs.

A revolution simply means great change, significant change, and that's how I'm defining it - great change for the better, brought about through non-violent means.

Over time, our emerging high-usage products will likely generate significant new revenue streams for Google as well as for our partners, just as search does today.

As a CEO, I had significant exposure to private equity, enough that I had in no way bought into the media's caricature: rapacious privateers who destroy companies.

It doesn't matter if you're black, white, gay, straight, come from different countries, different language... every single person is significant and is meaningful.

All actors have a significant amount of vanity about work, and necessarily so. Things they will do and won't do, and I've completely lost all of that. I don't care.

Who lives long and who dies prematurely, is the defining issue of our time. And I submit to you, there's a significant race dimension, it is basically class-driven.

France generates a significant part of its energy requirements from fission reactors and these have achieved a perfect safety record. We build ours all differently.

Evening the playing field for women workers is a matter of fairness and with women now providing a significant share of their family's income, it is a family issue.

You add one million citizens to the voting rolls in this state, that's a significant, significant difference. You do that nationwide, it's a significant difference.

Every man who knows how to read has it in his power to magnify himself, to multiply the ways in which he exists, to make his life full, significant and interesting.

Let's hope the Canadian public sector starts putting the blockchain on their agenda so we can see a significant difference in how government services are delivered.

There is absolutely no doubt in my mind that Saddam Hussein had and used significant weapons of mass destruction on his own people, both the Kurds and the Iranians.

Women were relegated to an inferior caste ... most dramatically with the coming of industrialization. 'Women's work' was segregated from significant human activity.

In New York City we have the biggest police force in the country. We have 35,000 uniformed officers. We're able to mass officers in significant numbers if we had to.

There are some very significant changes in the way the fluids are distributed in our body, the way our heart functions initially, and as well as our bone and muscle.

The day when the scientist, no matter how devoted, may make significant progress alone and without material help is past. This fact is most self-evident in our work.

Food manufacturing is an ideal candidate for targeted accelerated depreciation because the food industry, our biggest industry, creates significant flow-on benefits.

One of the significant things that's happened, which shouldn't be looked at as lightly as it might sound, is that women over 45, over 50, are now allowed to be sexy.

We are basically in the nicotine business. . . . Effective control of nicotine in our products should equate to a significant product performance and cost advantage.

While pimples are not as simple as too much milk or sugar in your diet, both have a significant impact. Nutritional deficiencies as well as excesses can worsen acne.

They emphasize the viewpoint that the protracted economic stagnation in Japan derives from incomplete economic adjustments to significant changes in relative prices.

Cap-and-trade is a dangerous policy fraught with the potential for significant corruption, and it would hurt my constituents and our economy by raising energy costs.

China never borrowed less than $3 billion a year during my tenure. They were the most significant client. They used the Bank not just for money but for the know-how.

HBO is not an advertiser-based model, it's a subscription model. So what's significant to HBO is not necessarily the debut of an episode, it's the cumulative numbers.

By the late 1980s, there was the beginning of awareness about a significant global landmine problem, and small steps were being taken to try to deal with the problem.

A lot of times, you get into it with your significant other, and you feel like, 'Oh my God, you are acting crazy.' I've heard that before - I'm sure a lot of us have!

You know, I'm a physician. I like to diagnose things. And, you know, I've diagnosed some pretty, pretty significant issues that I think a lot of people resonate with.

Women tend to be preservers of the social structure, of marriage. They don't want to upset their husbands or their significant others. They don't want to hurt people.

I've always been drawn to the four-leaf clover. It's deeply significant to my sister and me, so much so that we both have had it tattooed on the inside of our wrists.

I think malware is a significant threat because the mitigation, like antivirus software, hasn't evolved to a point to really mitigate the risk to a reasonable degree.

In doing that which we most enjoy, we will probably make our most significant contribution to society, and the contribution we make to society determines our rewards.

There's a certain kind of behavior in the Arab world that, to me, resembles the way young men behave when there is no significant influence from women in their lives.

It is an honor to serve your country, and if Mr. Trump called me to serve this great nation, I would proudly do whatever role he deems my talents are significant for.

Some people came up with story lines where Colonel Potter moves in with Klinger, and we become a 1950s' odd couple. I said, 'Come on, let's do something significant.'

We have cellphones and smartphones and iDevices and laptops and the ability to be perpetually connected. We never have to miss anything, significant or insignificant.

I am not a good example of an urban pastor. Because of the way I believe God calls me to use my time, I don't have significant relationships with most of my neighbors.

Systems, coaches, and directors or club presidents do not win games - players do, they are the only people who can make a significant difference once that game starts.

We are only beginning to learn what to say in a photograph. The world we live in is a succession of fleeting moments, any one of which might say something significant.

We've got to get rid of the stuff on the space station somehow. So we do have a pretty significant capability to bring back stuff on SpaceX that you might not imagine.

I think family businesses are still crucial for India's economy, but they need to professionalize. For young entrepreneurs, too, family should play a significant part.

When people are facing a severe illness or a major surgery, that may be one of the most significant opportunities for spiritual transformation that they will encounter.

Ultimately, my books are not about the politics, although the toil and the struggle and the wars in Afghanistan have a significant impact on the lives of my characters.

Seventy-five percent of women who smoke would like to quit, and yet only two to three percent quit every year... It's significant because we can help women quit smoking.

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