The first concert I ever went to was the Bee Gees.

I've seen Jaws [movie], like, 800 times. And I love it.

Sarah Silverman makes me laugh out loud every time I see her.

The comedy world is like a small pond; we all know each other.

Don't ever use duct tape on your privates. That's what I always tell people.

I was really good in high school, so in college I was going to be really bad.

I've stolen a lot. Let me think about the best thing I've stolen. Stolen a lot of hearts.

Most monuments are not something you're going to keep me out of. And I go to a lot of monuments.

Bigfoot loves celebrities. You just have to bring celebrities that Bigfoot loves. It would probably be just gorgeous women.

I have a thing that I do when I meet famous people, where I try to play it really cool. Sometimes I pretend like I don't know them.

I have done so many stupid commercials and terrible other little projects that never went anywhere and just ended up being terrible.

I didn't drink at all in school, so when I went to college, I went nuts. I was trying to catch up on all the partying I missed out on.

Even though the show is called 'Childrens Hospital,' we don't use kids a lot. They always want a juice box or a fruit roll up or a nap.

People always say, "When did you know you were funny?" They don't mean that in a bad way - this already makes me sound like such a jerk.

'Human Giant' was a kind of lightning in a bottle. A rare opportunity for us to write and create our own sort of thing, with very few restrictions.

That's a weird way to torture yourself. Just watch a movie, over and over, that you hate. That's really funny - that's probably exactly what hell is like.

I hate hospitals. Even if it's a joyful occasion when a friend gave birth. It's like, 'Oh, look at the beautiful baby.... and all the disease on the walls...'

I would host a show where I take famous people out into the woods every week to find Bigfoot. I would do that. And you know what? We would find him in like a week.

If you're going to steal a car, don't steal a mail vehicle. They don't mess around. I mean, have fun, steal all the cars you want, but don't steal a U.S. Mail vehicle.

I look up so much to those movies, 'Airplane!' and 'Naked Gun.' I think that stuff is so funny. I grew up just loving all that stuff and sort of idolizing Leslie Nielsen.

One of the coolest things was that, in 2007, I got to go to Iraq with Rob Riggle, Paul Scheer, and Horatio Sanz. We went over there to do some comedy shows with the U.S.O.

When you're expecting a baby, there's a lot you can plan for, but when it happens early you just have to jump into it. Whatever plans you had, everything goes out the window.

That's a very nice, generic-sounding question: "When did you know you were funny?" But it pre-supposes that I think I'm really hilarious. So that's kind of a loaded question.

I think there are a lot of really funny things in 'The Descendants,' but there're a lot of different tones in that movie, in the same way that 'Transparent' has a lot of different tones.

When I first started out, I kinda just wanted to do comedy stuff, and thankfully, I had a fair amount of success. I've been able to be on, I think, almost virtually every American sitcom.

We're going for the joke on 'Children's Hospital,' and we're going for the joke on 'The League.' It's fun to go between shows, but you have to mentally remind yourself what show you're on.

You know the awkward class photo when you're sitting there for your school picture and you're 14 or something and you've got braces, and you don't know how to smile, and you've got a hard-on.

Every other show that I'm on, they're always rushed, and you feel this pressure to hurry up and get out of the scene, but I don't feel that way on 'Transparent.' They like to linger in these scenes.

I kind of got really lucky a couple of years ago: I got to do a part in 'The Descendants,' in Alexander Payne's movie. I just had a small part, but I got to do a few scenes with my best friend George Clooney.

I have two brothers, and we used to always laugh at oblivious people. People who are so cocky and full of themselves that they just don't realize how stupid they are. And those kind of idiots really make me laugh.

I've gotten to go to a lot of places that I never would have been able to go and been able to meet a lot of people. And every now and then you'll be doing something and you're like, "I can't believe I get to do this."

We just haven't found Bigfoot because the world is big. And the woods are deep. The more TV shows that we can get where people go out looking for Bigfoot, the better our chances are. So let's get more of those shows going.

Paul McCartney chit-chats with you, he makes eye contact with you, he seems really interested in what you're saying. He really puts everyone else at ease and makes them feel good so they're not nervous, which I think is really cool.

Comedy people like other comedy people. People hang out and are friends and do shows together, and when you get something going like a TV show or a movie, you want your friends to be in it and make it funnier. That's just the way it should be.

A comedy scene can't really have two weirdoes in it. It doesn't make any sense that way, so you need someone to ground it and call out what's unusual about this person and this scene. Early on, I got pretty good at doing that, and I felt pretty comfortable doing that.

The world's so big, it's hard to pick one best friend. I like everyone in Venezuela, but in L.A., I hang out mostly with my comedy friends. Guys like Paul Scheer, Rob Riggle, Owen Burke, Ed Helms, Seth Morris - we all kind of came up together doing comedy in New York.

During the first season of 'Human Giant,' I remember the people at MTV were all over us. They hadn't really done a live-action short-film comedy show, so they didn't know what it was going to be, and they were worried. But after that, they let us do whatever we wanted.

There's no way to play it cool when you meet Paul McCartney. You just start sweating, you trip over your words. Everyone kind of reverts back to being a 10-year-old girl. You can't help it. He's one of the only people on planet Earth that everyone knows who he is. Everyone.

There's no way to play it cool when you meet Paul McCartney. You just start sweating; you trip over your words. Everyone kind of reverts back to being a 10-year-old girl. You can't help it. He's one of the only people on planet Earth that everyone knows who he is. Everyone.

George Clooney is exactly what you would expect. He's annoyingly good looking, insanely funny, and super smart. So you just feel really inferior around him all the time. You end up feeling really bad about yourself, but you walk away feeling really great about George Clooney.

The first concert I ever went to was the Bee Gees. I don't know if you remember the Bee Gees. My mom took me. I was little. But my mom was a big disco fan, and - my mom took me to the Bee Gees. Looking back now, it's pretty embarrassing if your first concert was with your mom.

Conan O'Brien's the best. I'm glad he's in L.A. because I want to move in with him. I was a guest on that show one time to promote 'Human Giant,' and he was the coolest, funniest guy. I was really impressed. He's also eight feet tall and can shoot lightning from his fingertips.

Can I play a southern character? You betcha. Can I do the voice of Tourist Dad and Carnival Barker? Ya betcha. Can I do Fix-It Felix? Ya betcha. But I don't want to just play southern characters, so I hide it; I bury it. I tamp it down like a secret. Like a dirty little secret.

My mom has this thing where if I'm doing anything doing dirty or crazy, she sniffs it out and yells at me. But the good thing is my mom doesn't have cable, and so much of the stuff I've done was on cable, so many times she'll miss it. I tend to gloss over the crazier things I shoot.

Alexander Payne is one of those directors who is completely in charge and knows exactly what he wants, which is really fun. It's fun when a director is very specific. He knows totally the tone that he's going for. It makes it easier than if everyone's just guessing and trying to figure it out.

I have a real problem now when I go onto Netflix: it takes me a half hour to pick something out. They've got to figure something out, whether it's their algorithm... Maybe if they had it curated like a video store: 'Will Ferrell recommends this movie' or 'Jennifer Lawrence recommends these 10 movies.'

I have a thing that I do when I meet famous people where I try to play it really cool. Sometimes I pretend like I don't know them.I was at this party and James Bond was there. Daniel Craig, but I think he goes by James Bond. Anyway, my wife is in love with him. He was in a tuxedo looking all James Bondish.

There was actually some serious time in front of the mirror, checking yourself out, checking out your shirt, checking out your pants.Combing that hair. Really putting some thought and effort behind it and it's astounding how terrible I used to make myself look. Still to this day I don't really know how to dress myself.

I grew up in the D.C. area, and I used to wear a Redskins jersey just walking around. I just had kind of a bowl haircut for a long time and no sense of style or personal hygiene. But the main thing was the haircut. You know, when you see a haircut of yourself from around 12 or 13, it's rough. I also had really bad acne.

'Axe Cop' is an animated show that just started on Fox that is based off the comic book series. And here's the hook: it's written by a 5-year-old. This 5-year-old has a brother who's, like, 28 and is in the business, and the little brother kept coming up with all these awesome stories for this character he dreamed up called Axe Cop.

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